Ford Motor Company is committed to helping build a better world, where every person is free to move and pursue their dreams. This will be advanced through the delivery of outstanding Electric Vehicles (EVs) with compelling connected vehicle services, Advanced Driver Assistance Systems (ADAS) and mobility solutions including self-driving Autonomous Vehicle (AV) technologies. These System-of-System (SoS) solutions will require that we leverage a diverse, global, agile Systems Engineering team that can extract actionable information from, and respond to, real-time connected customer experience data. This presentation will describe the Ford Model Based Systems Engineering (MBSE) journey. It will describe how our MBSE solutions have evolved and adapted to different system, software and technology complexity challenges, resulting in a Connected and Integrated, Agile, Model Based Systems Engineering & Simulation solution. The presentation will provide examples of how this Systems Engineering approach has been successfully applied to EV, ADAS and AV systems analysis and design. It will discuss some lessons learned on the trade-offs encountered when balancing “just enough” formalism (ontologies and standards) with scaled agility and risk. It will conclude by discussing the power of a harmonized systems engineering-enterprise-wide, AI/ML powered, digital-twin/digital thread solution. It is a fantastic time to be a system engineer. It is also an important time for us all to contribute where-ever and how-ever we can to help solve the many significant societal challenges.